Taskinen MR, Packard CJ, Boren J, et al. Nutrients 2019, 11, 1987; doi:10.3390/nu11091987 Download PDF Objective To review recent evidence linking excessive fructose consumption to health risk markers and development of components of the Metabolic Syndrome. Background Consumption of fructose, the sweetest of all naturally occurring carbohydrates, has increased dramatically in the last 40 years […]
Al-Ozairi E, Rivard CJ, Sanchez Gonzalez LG, et al. J Diabetes. 2019; 1– 8. https://doi.org/10.1111/1753-0407.12984 Download PDF Objective To examine the acute effects of an oral fructose tolerance test (OFTT) on serum uric acid concentrations in people with metabolic syndrome and type 2 diabetes. The effects of an oral glucose tolerance test (OGTT) on serum […]
BMJ Open 2019; 9:e024171. doi:10.1136/bmjopen-2018-024171 Ayoub-Charette S, Liu Q, Tauseef AK, et al. Download Research Study PDF Objective To conduct a systematic review and meta-analysis of prospective cohort studies to assess the relation of important food sources of fructose-containing sugars with incident gout and hyperuricaemia. Background Foods that increase net adenosine triphosphate (ATP) degradation including […]
Eur J Clin Nutr (2018) 72:1717-1723; https://doi.org/10.1038/s41430-018-0134-x — Rodrigues N, Peng M, Oey I, and Venn BJ. — Download PDF — Objective To assess the effects of partial replacement of sucrose with fructose on serum glucose, uric acid and blood pressure. Background Fructose has been shown to adversely affect plasma lipids and may predispose excessive […]
On April 18, Caliceti et al. published a review entitled “Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review” in Nutrients. The review focuses on the role of uric acid (UA) in cardio metabolic disorders and the relationship between fructose consumption, blood UA, and health outcomes. The authors first review purine metabolism including […]
A study entitled “Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents,” was recently published in the Journal of Hepatology. The purpose of the study was to identify the factors associated with non-alcoholic steatohepatitis (NASH) in children and adolescents with confirmed cases of non-alcoholic fatty liver disease (NAFLD). More […]
An article was recently published in Nutrition Reviews which aimed to summarize the current literature on the effects of fructose on reactive oxygen species (ROS) production and mitochondrial dysfunction in various tissues, particularly skeletal muscle, and identify research gaps for which future endeavors should address. First, reviewers provided an overview of the metabolic effects of […]
A recent systematic review and meta-analysis from The BMJ attempts to define a relationship between fructose intake and the development of gout and hyperuricemia. Researchers were only able to identify two prospective cohort studies which met their selection criteria; both of which pertained to fructose intake and gout but did not address incidence of hyperuricemia. […]
A recent systematic review and meta-analysis from The BMJ attempts to define a relationship between fructose intake and the development of gout and hyperuricemia. Researchers were only able to identify two prospective cohort studies which met their selection criteria; both of which pertained to fructose intake and gout but did not address incidence of hyperuricemia. […]
Fructose does not increase body weight, blood pressure, uric acid or insulin levels, and may improve glycemic control at normal consumption levels, according to research.
Fructose-rich beverages and risk of gout in women
The conclusion by Nguyen et al that higher sugar-sweetened beverage consumption (as proxy for dietary fructose) may affect cardiovascular risk factors like serum uric acid and blood pressure lacks significance for three reasons.
High serum uric acid concentration (hyperuricemia) has been studied for its relationship with multiple adverse health outcomes, such as metabolic syndrome. Intervention studies have produced inconsistent outcomes for the relationship between fructose intake and serum uric acid concentration.
Soft drinks, fructose consumption, and the risk of gout in men: prospective cohort study
