Heart Health

Important Food Sources of Fructose-Containing Sugars and Incident Hypertension: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies

By Heart Health

Liu Q, Ayoub-Charette S, Khan TA, et al. J Am Heart Assoc 2019; 8:e010977. DOI: 10.1161/JAHA.118.010977. Objective To assess the relation of important food sources of fructose-containing sugars with incident hypertension. Background Hypertension is a major risk factor for developing cardiovascular disease, and the global prevalence of hypertension has been increasing in the past decades. […]

Read More

Relation of Total Sugars, Sucrose, Fructose, and Added Sugars With the Risk of Cardiovascular Disease: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies

By Archives, Heart Health

Mayo Clin Proc 2019; 94(12):2399-2414; https://doi.org/10.1016/j.mayocp.2019.05.034 Khan TA, Mobushra T, Agarwal A, et al. Objective To determine the association of total and added fructose-containing sugars on cardiovascular disease (CVD) incidence and mortality. Background Much of the evidence supporting recommendations and policies to set upper-limits for added or free fructose-containing sugars derives from data on sugar-sweetened […]

Read More

Dietary Fructose and the Metabolic Syndrome

By Gout / Uric Acid, Heart Health, Liver Health

Taskinen MR, Packard CJ, Boren J, et al. Nutrients 2019, 11, 1987; doi:10.3390/nu11091987 Download PDF Objective To review recent evidence linking excessive fructose consumption to health risk markers and development of components of the Metabolic Syndrome. Background Consumption of fructose, the sweetest of all naturally occurring carbohydrates, has increased dramatically in the last 40 years […]

Read More

Maternal Exposure to High Fructose and Offspring Health

By Heart Health

Jia G, Hill MA and Sowers JR. Hypertension 2019; 74:499-501. DOI: 10.1161/HYPERTENSIONAHA.119.13017 Download PDF Objective This article is an editorial on a study recently published in the Hypertension journal entitled, “Maternal High-Fructose Intake Induces Multigenerational Activation of the Renin-Angiotensin-Aldosterone System”. Background Seong, et al. investigated whether maternal exposure to high fructose induces hypertension together with […]

Read More

Short-Term Isocaloric Intake of a Fructose- but not Glucose-Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight Healthy Subjects

By Gut Health, Heart Health, Liver Health

Mol Nutr Food Res, 2019; //doi: 10.1002/mnfr.201800868 Nier A, Brandt A, Rajcic D, et al. Download Research Study PDF Objective To determine if an isocaloric exchange of complex carbohydrates with fructose or glucose affects surrogate markers of liver health and vascular endothelial function in healthy normal weight young male and female adults. If so, the […]

Read More

The role of dietary sugars in health: molecular composition or just calories?

By Diabetes, Heart Health

J Clin Nutr 2019; //doi.org/10.1038/s41430-019-0407-z — Philip Prinz Eur — Download Research Study PDF — Objective: To conduct a review highlighting current literature to discuss the question of whether dietary sugars per se have an unfavorable health effect or if it is just the amount of calories that matters in the development of noncommunicable diseases […]

Read More

Study Summary of “Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity”

By Diabetes, Heart Health

For your information, a study entitled “Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity” was recently published in the Journal of Internal Medicine. The purpose of this study by Taskinen et al. was to determine the effects of fructose on liver fat development, body composition, dietary […]

Read More

Early Life Fructose Exposure and Its Implications for Long-Term Cardiometabolic Health in Offspring

By Diabetes, Heart Health

A review was recently published in Nutrients which examined the relationship between early life exposure to fructose and cardiometabolic outcomes in offspring. Reviewers cited a number studies which associated fructose intake with various health outcomes such as insulin resistance, elevated low density lipoprotein cholesterol, elevated triglycerides, obesity, type 2 diabetes, cardiovascular disease, non-fatal myocardial infarction, and […]

Read More

Methodological problems invalidate sugars differences

By Heart Health

In a recent paper, Le et al. reported finding differences between the two most commonly used sweeteners in the US, concluding that “compared with sucrose, HFCS [high fructose corn syrup] leads to greater fructose systemic exposure and significantly different acute metabolic effects.” Evidence in support of this conclusion was unconvincing, however, due to significant deficiencies in the experimental design.

Read More