Gout / Uric Acid

Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review

On April 18, Caliceti et al. published a review entitled “Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review” in Nutrients. The review focuses on the role of uric acid (UA) in cardio metabolic disorders and the relationship between fructose consumption, blood UA, and health outcomes. The authors first review purine metabolism including […]

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Study Linking Fructose Intake to Nonalcoholic Fatty Liver Disease

A study entitled “Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents,” was recently published in the Journal of Hepatology. The purpose of the study was to identify the factors associated with non-alcoholic steatohepatitis (NASH) in children and adolescents with confirmed cases of non-alcoholic fatty liver disease (NAFLD). More […]

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Uric Acid and Transforming Growth Factor in Fructose-induced Production of ROS in Skeletal Muscle

An article was recently published in Nutrition Reviews which aimed to summarize the current literature on the effects of fructose on reactive oxygen species (ROS) production and mitochondrial dysfunction in various tissues, particularly skeletal muscle, and identify research gaps for which future endeavors should address. First, reviewers provided an overview of the metabolic effects of […]

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Fructose Intake and Risk of Gout and Hyperuricemia, Systematic Review and Meta-analysis

A recent systematic review and meta-analysis from The BMJ attempts to define a relationship between fructose intake and the development of gout and hyperuricemia. Researchers were only able to identify two prospective cohort studies which met their selection criteria; both of which pertained to fructose intake and gout but did not address incidence of hyperuricemia. […]

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